DNA and RNA Structure Unit – Vocabulary, Protein Synthesis, Extraction, Pairing

Centered around the essential question, “How do the structures of DNA and RNA help them carry and pass on genetic information?”, this complete unit helps high school students explore the molecular basis of heredity through dynamic visuals, hands-on experimentation, literacy integration, and meaningful assessments.

Why Teachers Love This Resource:

• Builds deep understanding of DNA and RNA structure, function, base-pairing rules, and their roles in protein synthesis.
• Brings molecular biology to life with a hands-on strawberry DNA extraction lab that students love.
• Integrates real-world science literacy with reading comprehension tied to the scientists behind DNA and RNA discoveries.
• Includes differentiated quizzes to assess both foundational understanding and higher-order thinking.
• Everything’s ready to go—just print or project! Save time while delivering rigorous, standards-aligned instruction.

What’s Inside:

• Unit Pacing Guide – A clear and organized timeline with estimated time frames and a central essential question to keep instruction focused and intentional.
• Detailed Lesson Plan – Includes objectives, background knowledge, materials list, timing, and instructional steps to guide smooth, effective teaching.
• DNA & RNA Structure Presentation & Notes – Introduces key components of DNA and RNA molecules with clear visuals, vocabulary, and guided notes that promote comprehension and retention.
• DNA & RNA Reinforcement Activity – Strengthens understanding through a combination of visual labeling, transcription practice, and a literacy-based reading about scientists like Rosalind Franklin, Watson, and Crick.
• DNA Extraction Lab – An inquiry-based investigation where students extract DNA from strawberries to see the molecule they’ve been learning about, connecting abstract structure to real-world biology. Includes safety guidance, critical thinking questions, and reflection prompts.
• DNA & RNA Structure Quiz (Two Versions)
  Version A: Covers foundational knowledge including nucleotide structure, base pairing, and DNA vs. RNA differences.
  Version B: A more challenging version with higher-order questions, transcription application, and questions on molecular structure and function.
• Answer Keys and Teacher Guides – Every quiz and activity comes with detailed answers to save you time and support meaningful feedback.

Pro Tip: Help students connect what they’re learning to real-world science and medicine—like how DNA is used in forensics, ancestry testing, and genetic research. These real-life examples spark curiosity and make the content stick!

⭐ Looking for quality resources and time-saving tips for your secondary science classroom?
☑ Follow Spectacular Science on TPT
☑ Subscribe to My Newsletter
☑ Check Out My Blog
☑ Follow Me on Instagram

If you have any questions, please do not hesitate to ask.
Thanks for visiting!
Jessica